Humanized Liver Mice Model Market accounted for US$ 78.64 million in 2020 and is estimated to be US$ 133.72 million by 2030 and is anticipated to register a CAGR of 5.30%. The humanized liver mice model market refers to the market for the development, manufacturing, and sales of mice models that have been genetically modified to possess human liver cells. These models are used to study liver diseases, drug metabolism, and toxicity testing.
The humanized liver mice model market is expected to grow significantly in the coming years, driven by increasing demand from pharmaceutical and biotechnology companies for more accurate and reliable preclinical testing methods. Additionally, the rising prevalence of liver diseases, such as liver cancer and hepatitis, is expected to increase the demand for humanized liver mice models for research purposes.
Humanized Liver Mice Model Market Advantage:
- Accurate modeling of human liver function: Humanized liver mice models accurately mimic human liver function, making them a valuable tool for drug development and toxicology testing. These models can predict how a drug will be metabolized in humans, allowing for more accurate and efficient drug development.
- Cost-effective: Humanized liver mice models are cost-effective compared to other preclinical testing methods, such as clinical trials in humans or non-human primates. They also require fewer animals than traditional animal models, reducing the number of animals needed for research purposes.
- Ethical considerations: The use of humanized liver mice models can help reduce the need for animal testing in drug development and toxicology testing. This is because the models can accurately predict how a drug will be metabolized in humans, reducing the need for animal testing.
- Better understanding of liver diseases: Humanized liver mice models allow for a better understanding of liver diseases, such as liver cancer and hepatitis. These models can be used to study the underlying mechanisms of these diseases and to develop new treatments.
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Market Segmentation:
By Model:
- UPA-SCID
- FRG KO Mice
- TK-NOG Mice
By Application:
- Pharmacokinetics Studies
- In-vivo Liver Toxicity Testing
- Drug Metabolism Studies
Regional scope:
- North America– U.S., Canada
- Europe– UK, Germany, Spain, France, Italy, Russia, Rest of Europe
- Asia Pacific– Japan, India, China, South Korea, Australia, Rest of Asia-Pacific
- Latin America– Brazil, Mexico, Argentina, Rest of Latin America
- Middle East & Africa– South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa
Key players:
- Jackson Laboratory
- Crown Bioscience Inc. (JSR Life Science)
- Charles River Laboratories International
- Taconic Biosciences
- Ingenious Targeting Laboratory Inc
- Trans Genic Inc
- GenOway
- Creative Animodel
- Horizon Discovery Group plc.
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Key Questions answered in Humanized Liver Mice Model Market?
- What are the regulatory frameworks governing the use of humanized liver mice models in research, and how are they impacting the market?
The use of humanized liver mice models in research is subject to regulatory frameworks that vary by country and purpose of research. Compliance with these frameworks can impact the market by increasing costs and time required for regulatory compliance, but can also increase credibility and demand from pharmaceutical and biotechnology companies. Ethical considerations, such as appropriate human tissue sourcing and potential impact on human health and safety, also play a role in regulating the use of humanized liver mice models in research.
- What are the regional trends in the humanized liver mice model market, and which regions are expected to witness the highest growth in the coming years?
The humanized liver mice model market is growing globally, with North America and Europe being the largest markets due to the presence of major pharmaceutical and biotechnology companies. The Asia-Pacific region is expected to witness the highest growth in the coming years due to increasing investments in the biotechnology and pharmaceutical industries, as well as rising prevalence of liver diseases in the region. However, the market growth in all regions is subject to regulatory frameworks and ethical considerations regarding the use of humanized liver mice models in research.
- What are the major drivers, challenges, and opportunities in the humanized liver mice model market?
Major drivers of the humanized liver mice model market include increasing demand for personalized medicine, rising prevalence of liver diseases, and advancements in genetic engineering and biotechnology. Major challenges include ethical and regulatory considerations, high cost of development, and limitations in the predictive capacity of animal models. Opportunities include increasing collaborations and partnerships between pharmaceutical and biotechnology companies, as well as the development of novel technologies and applications for humanized liver mice models.
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